THE EFFECT OF THE INTRAVENOUS INJECTION OF GLUCOSE AND OTHER SUBSTANCES ON THE CONCENTRATION OF POTASSIu;M IN THE SERUM OF THE DOG

نویسندگان

  • JESSE L. BOLLMAN
  • FRANK C. MANN
  • EDWARD C. KENDALL
چکیده

Coincident with the drop in blood sugar produced by insulin, there occurs a marked drop in the inorganic phosphate and potassium in the blood serum and urine. This was shown by Harrop and Benedict in 1923 (1, 2) and by Briggs, Koechig, Doisy, and Weber (3). Kerr (4) showed also that the potassium that disappeared did not enter the corpuscles. Because an increased intake of carbohydrate will produce a decrease in inorganic phosphate in the serum, it might be expected that it would also produce a decrease in the concentration of potassium. To test this the effect of the administration of glucose and levulose to dogs has been studied; the influence of lactic acid and pyruvic acid, of epinephrine, and of fasting and pancreatectomy has also been investigated.

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تاریخ انتشار 2003